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1

Pediatric phase 1 trial and pharmacokinetic study of trebananib in relapsed solid tumors ADVL1115: A Children's Oncology Group phase 1 consortium report

Leary, Sarah E. S., Park, Julie R., Reid, Joel M., Ralya, Andrew T., Baruchel, Sylvain, Wu, Bing, Roberts, Timothy P. L., Liu, Xiaowei, Minard, Charles G, Fox, Elizabeth, Weigel, Brenda J., Blaney, Su

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 767 KB

english, 2017

2

3488 A comparison between the Rolling 6 and 3+3 dose escalation study designs for phase 1 clinical trials

Minard, Charles Gene, Rau, Rachel, Hilsenbeck, Susan, Weigel, Brenda J., Fox, Elizabeth, Adamson, Peter, Blaney, Susan

Journal:

Journal of Clinical and Translational Science

Year:

2019

Language:

english

File:

PDF, 63 KB

english, 2019

3

Genetics Underlying the Interactions between Neural Crest Cells and Eye Development

Weigele, Jochen, Bohnsack, Brenda L.

Journal:

Journal of Developmental Biology

Year:

2020

File:

PDF, 2.49 MB

2020

4

Retinoblastoma and Hirschsprung disease in a patient with interstitial deletion of chromosome 13

Weigel, Brenda J., Pierpont, Mary Ella M., Young, Terri L., Mutchler, Scott B., Neglia, Joseph P.

Journal:

American Journal of Medical Genetics

Year:

1998

Language:

english

File:

PDF, 61 KB

english, 1998

5

Osteosarcoma in the first decade of life

Rajaram Nagarajan, Brenda J. Weigel, Roby C. Thompson, John P. Perentesis

Journal:

Pediatric Blood & Cancer

Year:

2003

Language:

english

File:

PDF, 64 KB

english, 2003

6

Aprepitant for the control of chemotherapy induced nausea and vomiting in adolescents

Angela R. Smith, Tanya L. Repka, Brenda J. Weigel

Journal:

Pediatric Blood & Cancer

Year:

2005

Language:

english

File:

PDF, 62 KB

english, 2005

7

Cutaneous pseudolymphoma: An unusual presentation of a scalp mass

Nkechinyelu V. Nnebe, Carolyn Woon, Stephen Haines, Vanessa Dayton, Brenda J. Weigel

Journal:

Pediatric Blood & Cancer

Year:

2009

Language:

english

File:

PDF, 231 KB

english, 2009

8

Allogeneic hematopoietic cell transplantation (allogeneic HCT) for treatment of pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL)

Michael J. Burke, Qing Cao, Barb Trotz, Brenda Weigel, Ashish Kumar, Angela Smith, Michael R. Verneris

Journal:

Pediatric Blood & Cancer

Year:

2009

Language:

english

File:

PDF, 99 KB

english, 2009

9

Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers

Melissa A. Geller, Sarah Cooley, Peter A. Argenta, Levi S. Downs, Linda F. Carson, Patricia L. Judson, Rahel Ghebre, Brenda Weigel, Angela Panoskaltsis-Mortari, Julie Curtsinger, Jeffrey S. Miller

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

10

New paradigms for therapy for osteosarcoma

Rajaram Nagarajan, Denis Clohisy, Brenda Weigel

Journal:

Current Oncology Reports

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

11

Prolonged subcutaneous administration of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced hematologic malignancies

Brenda J. Weigel, Sarah Cooley, Todd DeFor, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Wei Chen, Bruce R. Blazar, Jeffrey S. Miller

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 78 KB

english, 2012

12

Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses

Brenda J. Weigel, Angela Panoskaltsis-Mortari, Miechaleen Diers, Melissa Garcia, Chris Lees, Arthur M. Krieg, Wei Chen, Bruce R. Blazar

Journal:

Experimental Hematology

Year:

2006

Language:

english

File:

PDF, 296 KB

english, 2006

13

A phase I trial of vorinostat and bortezomib in children with refractory or recurrent solid tumors: A Children's Oncology Group phase I consortium study (ADVL0916)

Jodi A. Muscal, Patrick A. Thompson, Terzah M. Horton, Ashish M. Ingle, Charlotte H. Ahern, Renee M. McGovern, Joel M. Reid, Matthew M. Ames, Igor Espinoza-Delgado, Brenda J. Weigel, Susan M. Blaney

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

14

Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study

Mossé, Yael P, Lim, Megan S, Voss, Stephan D, Wilner, Keith, Ruffner, Katherine, Laliberte, Julie, Rolland, Delphine, Balis, Frank M, Maris, John M, Weigel, Brenda J, Ingle, Ashish M, Ahern, Charlotte

Journal:

The Lancet Oncology

Year:

2013

Language:

english

File:

PDF, 116 KB

english, 2013

15

A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: A children's oncology group phase 1 consortium study

Hummel, Trent R., Wagner, Lars, Ahern, Charlotte, Fouladi, Maryam, Reid, Joel M., McGovern, Renee M., Ames, Matthew M., Gilbertson, Richard J., Horton, Terzah, Ingle, Ashish M., Weigel, Brenda, Blaney

Journal:

Pediatric Blood & Cancer

Year:

2013

Language:

english

File:

PDF, 133 KB

english, 2013

16

Phase 2 trial of cixutumumab in children, adolescents, and young adults with refractory solid tumors: A report from the Children's Oncology Group

Weigel, Brenda, Malempati, Suman, Reid, Joel M., Voss, Stephan D., Cho, Steven Y., Chen, Helen X., Krailo, Mark, Villaluna, Doojduen, Adamson, Peter C., Blaney, Susan M.

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 79 KB

english, 2014

17

Expression of FGFR3 and FGFR4 and clinical risk factors associated with progression-free survival in synovial sarcoma

Charbonneau, Bridget, Vogel, Rachel Isaksson, Manivel, J. Carlos, Rizzardi, Anthony, Schmechel, Stephen C., Ognjanovic, Simona, Subramanian, Subbaya, Largaespada, David, Weigel, Brenda

Journal:

Human Pathology

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

18

A therapeutic trial of decitabine and vorinostat in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia

Burke, Michael J., Lamba, Jatinder K., Pounds, Stanley, Cao, Xueyuan, Ghodke-Puranik, Yogita, Lindgren, Bruce R., Weigel, Brenda J., Verneris, Michael R., Miller, Jeffrey S.

Journal:

American Journal of Hematology

Year:

2014

Language:

english

File:

PDF, 538 KB

english, 2014

19

Phase 1 trial of temsirolimus in combination with irinotecan and temozolomide in children, adolescents and young adults with relapsed or refractory solid tumors: A children's oncology group study

Bagatell, Rochelle, Norris, Robin, Ingle, Ashish M., Ahern, Charlotte, Voss, Stephan, Fox, Elizabeth, Little, Anthony R., Weigel, Brenda J., Adamson, Peter C., Blaney, Susan

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 342 KB

english, 2014

20

Role of High-Dose Chemotherapy With Hematopoietic Stem Cell Rescue in the Treatment of Metastatic or Recurrent Rhabdomyosarcoma

Weigel, Brenda J., Breitfeld, Philip P., Hawkins, Douglas, Crist, William M., Baker, K. Scott

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2001

Language:

english

File:

PDF, 66 KB

english, 2001

21

Phase II study of cixutumumab in combination with temsirolimus in pediatric patients and young adults with recurrent or refractory sarcoma: A report from the children's oncology group

Wagner, Lars M., Fouladi, Maryam, Ahmed, Atif, Krailo, Mark D., Weigel, Brenda, DuBois, Steven G., Doyle, L. Austin, Chen, Helen, Blaney, Susan M.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 91 KB

english, 2015

22

Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: A report of the Children's Oncology Group

Burke, Michael J., Ahern, Charlotte, Weigel, Brenda J., Poirier, John T., Rudin, Charles M., Chen, Yingbei, Cripe, Timothy P., Bernhardt, M. Brooke, Blaney, Susan M.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 715 KB

english, 2015

23

A phase I trial and viral clearance study of reovirus (Reolysin) in children with relapsed or refractory extra-cranial solid tumors: A Children's Oncology Group Phase I Consortium report

Kolb, E . Anders, Sampson, Valerie, Stabley, Deborah, Walter, Alexa, Sol-Church, Katia, Cripe, Timothy, Hingorani, Pooja, Ahern, Charlotte Hsieh, Weigel, Brenda J., Zwiebel, James, Blaney, Susan M.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 352 KB

english, 2015

24

A phase 1 dosing study of ruxolitinib in children with relapsed or refractory solid tumors, leukemias, or myeloproliferative neoplasms: A Children's Oncology Group phase 1 consortium study (ADVL1011)

Loh, Mignon L., Tasian, Sarah K., Rabin, Karen R., Brown, Patrick, Magoon, Daniel, Reid, Joel M., Chen, Xuejun, Ahern, Charlotte H., Weigel, Brenda J., Blaney, Susan M.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 599 KB

english, 2015

25

Phase 2 trial of sorafenib in children and young adults with refractory solid tumors: A report from the Children's Oncology Group

Kim, AeRang, Widemann, Brigitte C., Krailo, Mark, Jayaprakash, Nalini, Fox, Elizabeth, Weigel, Brenda, Blaney, Susan M.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 105 KB

english, 2015

26

Chemotherapy Options for Poor Responders to Neoadjuvant Chemotherapy for Orbital Granulocytic Sarcoma

Gossai, Nathan, Cafferty, Rachel, Weigel, Brenda

Journal:

Current Treatment Options in Oncology

Year:

2016

Language:

english

File:

PDF, 296 KB

english, 2016

27

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

Zhou, Qing, Munger, Meghan E, Highfill, Steven L, Tolar, Jakub, Weigel, Brenda J, Riddle, Megan, Sharpe, Arlene H, Vallera, Daniel A, Azuma, Miyuki, Levine, Bruce L, June, Carl H, Murphy, William J, M

Year:

2015

Language:

english

File:

PDF, 484 KB

english, 2015

28

A phase 1 trial of temsirolimus and intensive re-induction chemotherapy for 2nd or greater relapse of acute lymphoblastic leukaemia: a Children's Oncology Group study (ADVL1114)

Rheingold, Susan R., Tasian, Sarah K., Whitlock, James A., Teachey, David T., Borowitz, Michael J., Liu, Xiaowei, Minard, Charles G., Fox, Elizabeth, Weigel, Brenda J., Blaney, Susan M.

Journal:

British Journal of Haematology

Year:

2017

Language:

english

File:

PDF, 140 KB

english, 2017

29

First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children’s Oncology Group Phase 1/Pilot Consortium

Balis, Frank M., Thompson, Patrick A., Mosse, Yael P., Blaney, Susan M., Minard, Charles G., Weigel, Brenda J., Fox, Elizabeth

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

30

Patterns of chemotherapy-induced toxicities and outcome in children and adolescents with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group

Gupta, Abha A., Chi, Yueh-Yun, Anderson, James R., Lyden, Elizabeth, Weigel, Brenda, Arndt, Carola, Meyer, William H., Rosenberg, Abby, Hawkins, Douglas S.

Journal:

Pediatric Blood & Cancer

Year:

2017

Language:

english

File:

PDF, 179 KB

english, 2017

31

A phase 1 study of the c-Met inhibitor, tivantinib (ARQ197) in children with relapsed or refractory solid tumors: A Children's Oncology Group study phase 1 and pilot consortium trial (ADVL1111)

Geller, James I., Perentesis, John P., Liu, Xiaowei, Minard, Charles G., Kudgus, Rachel A., Reid, Joel M., Fox, Elizabeth, Blaney, Susan M., Weigel, Brenda J.

Journal:

Pediatric Blood & Cancer

Year:

2017

Language:

english

File:

PDF, 321 KB

english, 2017

32

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group

Rudzinski, Erin R., Anderson, James R., Chi, Yueh-Yun, Gastier-Foster, Julie M., Astbury, Caroline, Barr, Frederic G., Skapek, Stephen X., Hawkins, Douglas S., Weigel, Brenda J., Pappo, Alberto, Meyer

Journal:

Pediatric Blood & Cancer

Year:

2017

Language:

english

File:

PDF, 498 KB

english, 2017

33

Historical time to disease progression and progression-free survival in patients with recurrent/refractory neuroblastoma treated in the modern era on Children's Oncology Group early-phase trials

London, Wendy B., Bagatell, Rochelle, Weigel, Brenda J., Fox, Elizabeth, Guo, Dongjing, Van Ryn, Collin, Naranjo, Arlene, Park, Julie R.

Journal:

Year:

2017

Language:

english

File:

PDF, 368 KB

english, 2017

34

Validation of genomic predictions for wellness traits in US Holstein cows

McNeel, Anthony K., Reiter, Brenda C., Weigel, Dan, Osterstock, Jason, Di Croce, Fernando A.

Journal:

Journal of Dairy Science

Year:

2017

Language:

english

File:

PDF, 261 KB

english, 2017

35

Phase 1 trial of ontuxizumab (MORAb-004) in children with relapsed or refractory solid tumors: A report from the Children's Oncology Group Phase 1 Pilot Consortium (ADVL1213)

Norris, Robin E., Fox, Elizabeth, Reid, Joel M., Ralya, Andrew, Liu, Xiaowei W., Minard, Charles, Weigel, Brenda J.

Journal:

Pediatric Blood & Cancer

Year:

2018

Language:

english

File:

PDF, 405 KB

english, 2018

36

Brentuximab vedotin with gemcitabine for paediatric and young adult patients with relapsed or refractory Hodgkin's lymphoma (AHOD1221): a Children's Oncology Group, multicentre single-arm, phase 1–2 trial

Cole, Peter D, McCarten, Kathleen M, Pei, Qinglin, Spira, Menachem, Metzger, Monika L, Drachtman, Richard A, Horton, Terzah M, Bush, Rizvan, Blaney, Susan M, Weigel, Brenda J, Kelly, Kara M

Journal:

The Lancet Oncology

Year:

2018

Language:

english

File:

PDF, 346 KB

english, 2018

37

The addition of cixutumumab or temozolomide to intensive multiagent chemotherapy is feasible but does not improve outcome for patients with metastatic rhabdomyosarcoma

Malempati, Suman, Weigel, Brenda J., Chi, Yueh-Yun, Tian, Jing, Anderson, James R., Parham, David M., Teot, Lisa A., Rodeberg, David A., Yock, Torunn I., Shulkin, Barry L., Spunt, Sheri L., Meyer, Wil

Journal:

Year:

2018

Language:

english

File:

PDF, 217 KB

english, 2018

38

A study of axitinib, a VEGF receptor tyrosine kinase inhibitor, in children and adolescents with recurrent or refractory solid tumors: A Children’s Oncology Group Phase 1 and Pilot Consortium Trial (ADVL1315)

Geller, James I., Fox, Elizabeth, Turpin, Brian K., Goldstein, Stuart L., Liu, Xiaowei, Minard, Charles G., Kudgus, Rachel A., Reid, Joel M., Berg, Stacey L., Weigel, Brenda J.

Journal:

Year:

2018

Language:

english

File:

PDF, 286 KB

english, 2018

39

Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children’s Oncology Group Study

Mossé, Yael P., Voss, Stephan D., Lim, Megan S., Rolland, Delphine, Minard, Charles G., Fox, Elizabeth, Adamson, Peter, Wilner, Keith, Blaney, Susan M., Weigel, Brenda J.

Journal:

Journal of Clinical Oncology

Year:

2017

Language:

english

File:

PDF, 760 KB

english, 2017

40

3488 A comparison between the Rolling 6 and 3+3 dose escalation study designs for phase 1 clinical trials

Minard, Charles Gene, Rau, Rachel, Hilsenbeck, Susan, Weigel, Brenda J., Fox, Elizabeth, Adamson, Peter, Blaney, Susan

Journal:

Journal of Clinical and Translational Science

Year:

2019

File:

PDF, 63 KB

2019

41

Phase II trial of the glycoprotein non-metastatic B-targeted antibody–drug conjugate, glembatumumab vedotin (CDX-011), in recurrent osteosarcoma AOST1521: A report from the Children's Oncology Group

Kopp, Lisa M., Malempati, Suman, Krailo, Mark, Gao, Yun, Buxton, Allen, Weigel, Brenda J., Hawthorne, Thomas, Crowley, Elizabeth, Moscow, Jeffrey A., Reid, Joel M., Villalobos, Victor, Randall, R. Lor

Journal:

European Journal of Cancer

Year:

2019

Language:

english

File:

PDF, 419 KB

english, 2019

42

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1â2 trial

Davis, Kara L, Fox, Elizabeth, Merchant, Melinda S, Reid, Joel M, Kudgus, Rachel A, Liu, Xiaowei, Minard, Charles G, Voss, Stephan, Berg, Stacey L, Weigel, Brenda J, Mackall, Crystal L

Journal:

The Lancet Oncology

Year:

2020

Language:

english

File:

PDF, 498 KB

english, 2020

43

Treatment of generalized infantile myofibromatosis with sorafenib and imatinib: A case report

Bidadi, Behzad, Watson, Andrea, Weigel, Brenda, Oliveira, Andre, Kirkham, Justin, Arndt, Carola

Journal:

Pediatric Blood & Cancer

Year:

2020

File:

PDF, 481 KB

2020

44

Prognostic Factors for Development of Subsequent Metastases in Localized Osteosarcoma: A Systematic Review and Identification of Literature Gaps

Basile, Patrick, Greengard, Emily, Weigel, Brenda, Spector, Logan

Journal:

Year:

2020

File:

PDF, 1.32 MB

2020

45

Safety and efficacy of gammaâsecretase inhibitor nirogacestat (PFâ03084014) in desmoid tumor: Report of four pediatric/young adult cases

Takahashi, Takuto, Prensner, John R., Robson, Caroline D., Janeway, Katherine A., Weigel, Brenda J.

Journal:

Pediatric Blood & Cancer

Year:

2020

File:

PDF, 358 KB

2020

46

Racial and Ethnic Differences in Sarcoma Incidence Are Independent of Census-Tract Socioeconomic Status

Diessner, Brandon J., Weigel, Brenda J., Murugan, Paari, Zhang, Lin, Poynter, Jenny N., Spector, Logan G.

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2020

File:

PDF, 624 KB

2020

47

Safety, tolerability and pharmacokinetics of crizotinib in combination with cytotoxic chemotherapy for pediatric patients with refractory solid tumors or anaplastic large cell lymphoma (ALCL): a Childrenâs Oncology Group phase 1 consortium study (ADVL1212)

Greengard, Emily, Mosse, Yael P., Liu, Xiaowei, Minard, Charles G., Reid, Joel M., Voss, Stephan, Wilner, Keith, Fox, Elizabeth, Balis, Frank, Blaney, Susan M., Adamson, Peter C., Weigel, Brenda J.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2020

File:

PDF, 715 KB

2020